The Sooners, however, have largely been dominant against the rest of the Big 12. Kansas State has won three out of four and covered the spread in each of those four contests. Oklahoma might have taken itself out of playoff contention with a loss to Kansas State last week but Chris Klieman's Wildcats have generally just had Oklahoma's number the last few years.

18 Oklahoma (-5) goes on the road and covers against TCU at noon ET on Saturday. One of the college picks the model is high on in Week 5: No.

Top college football predictions for Week 5 Now, it has turned its attention to the latest Week 5 college football odds from Caesars and locked in picks for every FBS matchup. Anyone who has followed it has seen huge returns. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. The SportsLine Projection Model simulates every FBS college football game 10,000 times. Before locking in any Week 5 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's advanced computer model. The Wolverines are 10.5-point favorites on the road against the unranked Iowa Hawkeyes according to the Week 5 college football lines. 4 Michigan would also love to get back into the CFP after an embarrassing 34-11 loss to Georgia in the semifinals last year. But after nearly losing as a 21-point favorite in its last road game against Texas, can you trust Alabama enough to include the Tide in your Week 5 college football bets?

ET, CBS) according to the latest Week 5 college football odds from Caesars Sportsbook. 2 Alabama is a 17-point favorite on the road over No. Since the College Football Playoff was implemented in 2015, Alabama has made at least the semifinals every season but one, and the Crimson Tide will look to continue plowing towards their eight appearance in nine years when they take on the Arkansas Razorbacks on Saturday.

College football odds lines